Funding

ERC Proof of Concept Grant for TRANSLATE: Translation-Guided RNA engineering Platform for Cardiac Haploinsufficiency

We congratulate Prof. Leo Kurian on being awarded a  European Research Council (ERC) Proof of Concept Grant for the project TRANSLATE.

Building on discoveries from the ERC Consolidator Grant TRANSCEND, TRANSLATE combines systems RNA biology, quantitative modeling, and machine learning to explore how the selective control of mRNA translation can be harnessed for therapeutic intervention. The project seeks to develop RNA engineering strategies for the targeted control of mRNA translation as a new therapeutic modality, asking whether the regulatory logic that determines which mRNAs are translated, when, and how much, can be redirected to restore biological function.